Andrews was last seen in Pea Ridge, Arkansas on November 18, 2006. She told her mother she was going to the Pea Ridge Church of the Nazarene to look at some clothes the church was giving away. She never returned and has never been heard from again. She was last seen getting into an older model brown pickup truck. Her mother reported her missing that evening.

Andrews was originally thought to be the possible victim of an abduction, but now she is believed to have left of her own accord. Prior to her disappearance she had had problems with being bullied at school and she was worried about being a financial burden to her family. She may still be in the local area; there have been unconfirmed sightings of her in northwest Arkansas since her disappearance. Her case remains unsolved.