Boozer was last seen left his residence on foot in the 5800 block of Montrose in Philadelphia, Pennsylvania at 8:00 a.m. on June 21, 2006 to take the train to a doctor's appointment at Wills Eye Hospital. He arrived safely at the doctor's office in the vicinity of 8th Street and Walnut and left afterwards at 11:30 a.m. He never made it home and has never been heard from again. He was carrying a brown wallet at the time of his disappearance.

Prior to his disappearance, Boozer had begun falling asleep during the daytime. Authorities believe it's possible he fell asleep on the train, missed his stop and became lost and disoriented. Boozer's wife describes him as an extremely shy man who would be unlikely to seek out attention even if he needed help. She reported him as a missing person at 5:00 p.m. on the day of his disappearance. Due to his medical conditions, there is fear for Boozer's safety. He has gone missing before. Boozer was not having any family problems at the time of his June 2006 disappearance. He is a World War II veteran and worked for the Campbell's Soup company for 40 years. His case remains unsolved.