Clement was last seen at her residence in the 2700 block of Sorrel Avenue in Baton Rouge, Louisiana on April 7, 1963, the day after Easter. She called her estranged husband and asked him to baby-sit their two young children while she went to look for a job. Clement's husband picked the children up and never saw or heard from his wife again.

A neighbor called Clement's brother a week later to tell him she had vanished. Clement's brother broke into her house, which was locked, and found a mildewed basket of washed clothes in the laundry room. Nothing was missing from the house except Clement's Easter clothes and the bedspread in her room. She was a writer at the time of her disappearance; she had written several short stories and was working on a novel. Clement's case remains unsolved.