Drzewiecki was last seen in Odessa, Texas on September 13, 1982. She was employed at the Doll's House, a club on Andrews Highway, at the time. She had been dancer there, but had taken the position of waitress by the time of her disappearance. Drzewiecki went to the Doll's House that evening to discuss a work matter. While she was there she had one alcoholic drink, then left, saying she had to get home to her daughter. She has never been heard from again.

Drzewiecki's pickup truck was found abandoned on the south end of Odessa a week after her disappearance, and was towed to the home she shared with her husband. The Doll's House is on the north side of the city, and Drzewiecki lived in the central part of town.

Foul play is suspected in Drzewiecki's case, but little evidence is available as to her fate. She disappeared just days after the birth of her daughter.