Epps was last seen in Wichita, Kansas on March 21, 2007. He left to see a friend and never returned home. At the time of his disappearance, he drove a white 1996 Chevrolet Tahoe with a U-Haul bumper sticker, a tailgate, black rims, and large tires. He last used his cellular phone at 5:55 p.m. on the day he went missing. Epps has never been heard from again. On March 23, his vehicle turned up at the Greenmill Restaurant at Kellog and Rock Road, with his phone locked inside.

In July 2007, authorities charged Jeffrey Salas, also known as Jeffrey Hopper, with Epps's murder. Investigators stated Salas and Epps participated in criminal activity together, but they have not disclosed their evidence against Salas. Early on in the investigation, police considered him a suspect. Salas awaits trial.

Epps left behind two young sons whom he shared a close bond with and saw daily. His family stated he did not use illicit drugs or drink alcohol. His body remains missing, but authorities suspect foul play in his case due to the circumstances involved.