Mary was last seen at approximately 10:00 p.m. on May 29, 2002 in Lucedale, Mississippi. She was in the 200 block of Clarence Bonnett Road at the time of her disappearance. She has never been heard from again. She was reported missing by her mother and older sister.

Mary's husband, Jonathan Loper, was arrested on the day of her disappearance for manufacturing marijuana. Authorities stated that Jonathan refused to cooperate with police in regards to his wife's disappearance. He was incarcerated for a time after Mary went missing, and tried without success to escape from jail. After his release Jonathan was arrested for aggravated assault.

A search of the area failed to produce any evidence as to Mary's whereabouts. She is the mother of three small sons, who are now in the custody Jonathan's parents. Mary's case remains unsolved. Authorities say there is no evidence of foul play, but they are uncertain as to what happened to her.

Some agencies may list May 30, 2002 as the date of Mary's disappearance.