Miller lived with her mother in Williamsport, Pennsylvania in 1992. Her mother described her as a naive, trusting individual with some learning disabilities. Miller's mother stated her daughter's behavior changed a few months prior to her disappearance and she thinks she may have become involved with drugs. In the fall of 1992, Miller had an argument with her mother and went to stay with her boyfriend at the Academy Apartments in Bellefonte, Pennsylvania. She was last seen on October 24, 1992, when she, her boyfriend and his nephew got into a vehicle en route to Williamsport. They were riding in a delapidated brown/maroon 1982 Datsun 210. Miller may have been carrying a denim purse at the time. She has never been heard from again. Although Miller and her mother weren't getting along in 1992, she was still close to her siblings and her family doesn't believe she would have left without telling them. They reported her missing after a month passed without them hearing from her.

Authorities believe Miller was the victim of a homicide. The police interviewed her boyfriend about her disappearance in 2008, and he denied having harmed her. About six months after the interview, he took his own life. The boyfriend's nephew claimed at one point that Miller had been murdered and actually lead investigators to the supposed burial site, but no human remains were found there and the nephew now refuses to cooperate with the investigation. Miller's disappearance remains unsolved.