Sprague was last seen in leaving her place of employment, a nightclub in the 300 block of Madison Avenue in Daytona Beach, Florida, on September 11, 1979. She had gone to the nightclub at 10:00 p.m. the previous day to pick up her paycheck and have a few drinks. Afterwards she argued with her boss and left the club at 1:00 a.m. The cabdriver who picked her up said they had to elude a truck that appeared to be following them. Sprague has never been heard from again.

Sprague worked as an exotic dancer at the time of her disappearance, and had a young son. Her loved ones describe her as a responsible individual who was in a stable relationship in 1979, and would not have left of her own accord. Sprague's son was later adopted by another family and has since died. Many of Sprague's other relatives, including her mother, are also deceased. Her case remains unsolved.