Wilson was last seen at the Lake Monroe Inn on U.S. 17-92 in Deltona, Florida at approximately 9:00 p.m. on December 4, 1976. She and her husband were eating at the inn with friends when Wilson became ill. Her husband took her outside to their car and left her there, with the motor running and the heat turned on, while he finished eating. When he returned a few minutes later, Wilson and the car were gone. The vehicle is a brown and yellow 1973 Chevrolet Impala with the license plate number 8W-3270. Wilson knows how to drive and had a valid driver's license in 1976, but her husband stated she was afraid to drive at night and he didn't believe she would have driven away on her own.

Authorities believe Wilson may have been abducted. Foul play is suspected in her case, which remains unsolved. She resided in the 1000 block of Persian Drive in Deltona at the time of her disappearance.